A new study conducted on teenagers in the US has uncovered distinct differences in brain structures between those who began using substances, such as alcohol and cannabis, before the age of 15 and those who did not. The research, led by scientists from Washington University in St. Louis, suggests that certain brain features might influence the likelihood of initiating substance use at a young age.

The study found that teens who used substances exhibited differences in brain structures, such as a larger overall brain size and a thinner prefrontal cortex, compared to their peers who abstained from substances. Interestingly, the research also pointed out that some of these brain differences were possibly present even before the teens began using substances, raising the possibility that these structural traits could contribute to the risk of substance use initiation.

Researchers emphasized that while these brain differences may play a role, other factors, including genetic and environmental influences, also likely contribute to the decision to start using substances during adolescence.

The study sheds new light on the complex relationship between brain development and substance use, providing valuable insights for future research on prevention and intervention strategies.